Maintain

Maintain The Functional Integrity Of The Skin Barrier

Skin hydration with ad libitum moisturiser use is a first-line treatment strategy1-5. Moisturisers help to support the functional integrity of the skin barrier by retaining moisture in the skin, which is important between flare-ups1-5. However, conventional moisturisers do not address the underlying lipid deficiency in eczematous skin and form a more superficial occlusive barrier on the skin1. Therapeutic moisturisers containing ceramides, free fatty acids and cholesterol – often termed ‘physiological moisturisers’ – can help to produce extracellular lipid bilayers to restore the skin barrier composition in comparison to a standard moisturiser6.

To help manage eczema symptoms, it is important to support the skin’s barrier function by using moisturising products that are designed to help reduce transepidermal water loss (TEWL), enabling skin hydration and reducing dryness and itch.

A compromised skin barrier can result in7,8.

Considerations When Choosing Appropriate Daily Skincare Products For Eczema Skin

Considerations when choosing appropriate daily skincare products for eczema skin.

QV Dermcare Eczema Daily

In a randomised, double-blind, placebo-controlled, single centre comparative trial conducted on clinically-diagnosed moderate eczema adults, QV Dermcare Eczema Daily range was found to significantly improve transepidermal water loss (TEWL), skin hydration and assist in reducing itch in eczematous skin compared with control1.


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QV Dermcare Eczema Daily

In a randomised, double-blind, placebo-controlled, single centre comparative trial conducted on clinically-diagnosed moderate eczema adults, QV Dermcare Eczema Daily range was found to significantly improve transepidermal water loss (TEWL), skin hydration and assist in reducing itch in eczematous skin compared with control1.

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Our Maintenance Range

QV Dermcare Eczema Daily Wash & Cream: Helps relieve the symptoms of mild to moderate eczema.

References

1. Spada F et al. Dermatol Ther 2021;34(4):e14970. (n=100) Study sponsored by Ego Pharmaceuticals Pty Ltd.

2. Nemeth V, Evans J. Eczema. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan. 

3. Zeichner JA, Del Rosso D. J Clin Aesthet Dermatol. 2016; 9(12):26–32.

4. Schneider L, et al. J Allergy Clin Immunol. 2013;131(2):295-9.e1–27.

5. Dermatitis In: eTG Dermatology [Internet]. Available from: https://tgldcdp.tg.org.au/guideLine?guidelinePage=Dermatology&frompage=etgcomplete

6. Chamlin SL, et al. J Am Acad Dermatol 2002;47(2):198–208.

7. Matsui T, Amagai M. Dissecting the formation, structure and barrier function of the stratum corneum. Int Immunol 2015;27(6):269–80.

8. Harding CR. The stratum corneum: structure and function in health and disease. Dermatol Ther 2004;17(s1):6–15.

9. Holden C, English J, Hoare C, Jordan A, Kownacki S, Turnbull R, et al. Advised best practice for the use of emollients in eczema and other dry skin conditions. J Dermatolog Treat 2002;13(3):103–6. 

10. Bourke J, Coulson I, English J. Guidelines for the management of contact dermatitis: an update. Br J Dermatol 2009;160:946-954. 

11. Draelos ZD. The science behind skin care: Cleansers. J Cosmet Dermatol 2018;17(1):8–14

12. Zeichner JA and Del Rosso D. Multivesicular Emulsion Ceramide-containing Moisturizers: An Evaluation of Their Role in the Management of Common Skin Disorders. J Clin Aesthet Dermatol. 2016; 9(12):26-32.

13. Fluhr J, Gloor M, Lehmann L, Lazzerini S, Distante F, Beradesca E. Glycerol accelerates recovery of barrier function in vivo. Acta Derm Venereol 1999;79:418–421.

14. Wehr RF, L K. Considerations in Selecting a Moisturizer. Cutis 1987;39:512–515.

15. Pedersen LK, Jemec GBE. Plasticising effect of water and glycerin on human skin in vivo. J Dermatol Sci 1999;19:48–52.

16. Rawlings AV, Davies A, Carlomusto M, et al. Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function. Arch Dermatol Res. 1996;288:383-390 

17. Soma Y, Kashima M, Imaizumi A, Takahama H, Kawakami T, Mizoguchi M. Moisturizing effects of topical nicotinamide on atopic dry skin. Int J Dermatol. 2005;44:197-202.